CAS Key Laboratory of Nuclear Materials and Safety Assessment of the Chinese Academy of Sciences was established in August 2014 and was formed by a research team of basic research and applied research on nuclear materials and safety assessment in IMR. Currently, the laboratory is the only unit specializing in nuclear materials and safety assessment at CAS. It has unique advantages in research and development of nuclear materials, manufacture of key structural components in nuclear power plants, study of materials degradation in high-temperature high-pressure water, and the design and manufacture of corrosion test equipment in high-temperature high-pressure water. In the last five years, the laboratory has published 231 peer-reviewed papers and been granted 63 patents. By conducting breakthrough research and developing innovative technology, the laboratory aims to support the rapid development of nuclear power plants in China and contribute to society.